Research Technician II

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

 

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

 

The Nabet laboratory is seeking a bright and highly motivated Research Technician II to provide high-level technical support for ongoing research efforts. The goals of our research program are to develop strategies to target cancer drivers by controlling protein homeostasis to gain new biological insights into clinically relevant targets and to advance new therapeutic strategies in cancer. The Nabet laboratory develops and deploys innovative chemical biology technologies such as the dTAG system to rapidly eliminate target proteins for therapeutic target discovery and validation (Nabet et al., Nature Chemical Biology 2018; Nabet et al., Nature Communications 2020; Li et al., Journal of Clinical Investigation 2024). The Nabet laboratory is highly collaborative and works extensively with medicinal chemists to develop inhibitors and degraders for cancer drug targets (Koide et al., ChemBioChem 2023; Li et al., European Journal of Medicinal Chemistry 2022). We are committed to supporting the next-generation of scientists and believe in collaborative science (Nabet, ChemBioChem 2021). This is an exceptional opportunity to join a new team that is pushing the boundaries of cancer chemical biology.

We are seeking candidates to contribute to both conceptual and technical aspects of the project with the ability to work independently and part of a dynamic team. The candidate will develop engineered cancer model systems and evaluate small molecules in these models as well as assist in lab managerial duties including the set-up, operation and maintenance of laboratory instruments and equipment. The candidate will become involved with all the steps of research being completed by the group and will have the opportunity to present their research during meetings and be involved in the publishing of scientific abstracts and papers. The experience gained in the laboratory will be useful for pursuing diverse careers including those as a researcher or physician.

 

Additional responsibilities include:

• Cell and molecular biology techniques including western blotting, immunoprecipitation, cloning, PCR, qPCR, sterile tissue culture, virus preparation, DNA/RNA isolation, CRISPR/Cas9-mediated genome editing, flow cytometry, and cell sorting.
• Murine modeling work including animal handling, compound administration, and dissection.
• Use computers, computer-interfaced equipment, robotics, or high-technology applications to perform work duties as well as equipment that requires setup, calibration, maintenance, and troubleshooting.
• Analyze and interpret experimental data and summarize findings for presentations, grants, pre-prints, and publications.
• Provide intellectual and interactive commitment to the position by keeping up with appropriate literature and research publications.
• Monitor and order supplies for the lab.
• Maintain organized and complete lab records and inventories.

MINIMUM QUALIFICATIONS:

• BA/BS in biology, molecular biology, biochemistry, chemistry, or related fields.
• 2 years of experience working in a lab outside of school coursework

PREFERRED QUALIFICATIONS:

• Highly motivated and intellectually curious.
• A solid background knowledge in cell and molecular biology and/or cancer biology.
• Excellent written and verbal skills.
• Exceptional attention to detail and thorough in completing work tasks.
• Experience with standard laboratory techniques such as tissue culture, western blotting, immunoprecipitation, extraction and analysis of DNA and RNA, PCR, and cloning.
• Experience in bioinformatics and/or mouse modeling is a plus.
• Ability to maintain an organized laboratory notebook and computer files with a working knowledge of data management, word processing, and graphic software (e.g. Microsoft office, Graphpad/PRISM) is preferred.

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The hourly pay range for this position is from $26.48 to $37.70 and pay offered will be based on experience and qualifications.

 

Fred Hutchinson Cancer Center offers employees access to a retirement savings plan, an employee assistance program, paid sick leave (1 hour for every 30 hours worked), and prorated paid holidays (up to 13 days per year).

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to Human Resources at hrops@fredhutch.org or by calling 206-667-4700.