A Post-Doctoral Research Fellow position is available in the lab of David MacPherson at Fred Hutch, which is focused on the biology of small cell lung cancer (SCLC). We apply functional screens and analyses of genetically engineered mouse (GEM) and patient derived xenograft (PDX) models towards understanding how genetic alterations alter the biology of SCLC and alter sensitivity towards conventional and novel therapies. Projects use cutting-edge genomics and CRISPR screening approaches and we work closely with thoracic oncologist collaborators at Fred Hutch to help translate basic findings to the clinic. Some of these directions are supported by an NIH Lung Cancer SPORE award that promotes translational lung cancer research.
The specific project will be developed by both the candidate and Dr. MacPherson based on areas of shared interest. Major areas of lab research include 1) understanding response and resistance to therapy using a combination of functional screens, in vivo modeling and genomic analyses of sequentially captured patient samples 2) developing innovative liquid biopsy assays to link patient phenotypes to clinical responses and 3) modeling biologically distinct subsets of SCLC using mouse and PDX systems. Projects are typically multidisciplinary and can involve co-mentorship where appropriate. The position will require both independent research as well as the ability to collaborate closely with colleagues.
Other Expectations
MINIMUM QUALIFICATIONS:
The annual base salary range for this position is from $77,976 to $95,014 and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance.
Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).
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