Post-Doctoral Research Fellow

Job ID
27216
Type
Regular Full-Time
Location
US-WA-Seattle
Category
Laboratory Research Sciences

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.


With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.


At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

 

The Paulovich Lab at Fred Hutch (https://research.fredhutch.org/paulovich/en.html) is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine via patient selection and characterization of novel therapeutic targets. The lab has a major focus on mass spectrometry (MS)-based proteomics (both untargeted and targeted, multiple reaction monitoring), as well as integrating proteomic data with genomic data. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.

 

This is a terrific opportunity within the Paulovich lab for a highly motivated full-time Post-Doctoral Research Fellow to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing bench-level experiments in support of proteomic, genomic, and transcriptomic analyses of clinical and preclinical biospecimens. The ideal candidate will be able to work as part of a team as well as independently to follow established standard operating protocols (SOP) in a CLIA/CAP laboratory environment.

Responsibilities

  • Perform molecular biology and biochemistry experiments on human and animal biospecimens and cell lines
  • Perform tissue culture experiments and maintain cultures and reagents in a sterile environment
  • Work with antibodies (immunoaffinity purification, immobilization on solid supports, perform ELISA to screen hybridomas)
  • Assist in generation of mass spectrometry (MS)-based proteomic data
  • Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
  • Follow standard operating protocols (SOP) in a CLIA/CAP laboratory environment including participating in annual competency and proficiency testing
  • Collaborate effectively with an interdisciplinary team spanning expertise in medicine, biology, analytical chemistry, and statistics
  • Maintain laboratory equipment, records, research results files, and databases
  • Assist with written progress reports and development of standard operating protocols (SOPs)
  • Assist with writing scientific manuscripts (in peer-reviewed journals)
  • Perform other duties as required

Qualifications

MINIMUM QUALIFICATIONS:

  • Ph.D. degree in Protein Chemistry, Analytical Chemistry, Biochemistry, or related discipline
  • The work is rigorously quantitative, and exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintain records
  • The position includes drafting manuscripts for publication and, thus a demonstrated track record of authorship in peer-reviewed journal publications, as well as excellent English written communication skills
  • The position includes giving oral presentations at local meetings, on consortium teleconferences, and at national and international meetings; thus excellent English oral communication skills
  • Ability to work as part of an interdisciplinary team
  • Proficiency with MS Office programs (Word, Powerpoint, Excel, and Access)
  • Ability to multi-task efficiently in a highly interactive team environment
  • Must be comfortable in a milestone-driven environment, with quarterly objectives
  • Willingness to learn new techniques
  • Passion for translating biology into clinical solutions
  • Strong work ethic

PREFERRED QUALIFICATIONS:

  • Previous tissue culture experience and sterile technique
  • Previous experience in a CLIA/CAP or similar clinical lab environment
  • Previous work in proteomics, genomics, and functional biology

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.


The annual base salary range for this position is from $67,728 to $100,000 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to Human Resources at hrops@fredhutch.org or by calling 206-667-4700.

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