Research Techician I (Hourly)

Job ID
24352
Type
Regular Full-Time
Location
US-WA-Seattle
Category
Laboratory Research Sciences

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

 

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

 

The Termini Lab is recruiting a highly motivated Research Technician I to join our team. Our lab focuses on understanding how hematopoietic stem cells regenerate after stress and how these pathways are manipulated during acute myeloid leukemia. The Termini Lab combines basic cell biology with translational applications using pre-clinical mouse models and primary patient samples to evaluate hematopoietic stem cell regeneration from a multitude of scales. Specifically, we utilize flow cytometry, super-resolution imaging, and basic biochemical techniques coupled with in vivo stem cell transplantation assays to quantify stem cell and niche function.

 

The candidate will assist the Principal Investigator (PI) in performing research and contributing to daily laboratory operations. The successful candidate will work with the PI and other lab members to perform cutting-edge research rooted in cell biology, molecular genetics, glycobiology, and immunology to evaluate stem cell function at the nano, cellular, microenvironmental, and organismal scales. The Research Technician I will perform experiments, maintain the laboratory, assist in managing the mouse colony, analyze data, receive mentorship from the PI, and be a part of an inclusive environment that supports creativity, professional development, and scientific discovery. 

Responsibilities

This position works under the guidance of, and in conjunction with the PI or higher-level laboratory personnel, in accomplishing the goals of the laboratory, including:

  • Perform experiments and assist with maintaining daily laboratory operations/organization.
  • Administrative responsibilities related to laboratory safety, ordering supplies, performing basic laboratory and equipment maintenance, and maintaining databases.
  • Perform bench-level experiments that involve operating analytical instruments (flow cytometer, cell sorter, PCR machine), recovering, compiling, and verifying the accuracy of research data, performing calculations, preparing graphs, and performing statistical analyses.
  • Perform mouse handling, including coordinating/performing basic animal care, setting up breeder pairs, weaning mice, genotyping mice, etc.
  • The successful candidate will be involved in the following experimental techniques:
    • In vivo mouse models of hematopoietic stem cell regeneration (transplants, peripheral blood analysis, radiation treatment, chemotherapy administration)
    • Basic cell culture of mammalian cell lines and primary cells
    • Tissue isolation of hematopoietic and niche cells
    • Flow cytometric immunophenotyping and fluorescence-activated cell sorting of human and mouse cells
    • Tissue preparation for histological analysis using microscopy (brightfield, confocal)
    • Immunofluorescence and microscopy
    • Basic biochemistry (protein isolation, Western blotting, immunoprecipitation, ELISA)
    • RNA expression analysis (RNA extraction, cDNA creation, qRT-PCR analysis, RNA sequence analysis)
    • Flow cytometric analysis (protein expression, cell cycle status, cell death status, etc.)
    • Lentiviral transduction of primary mammalian cells and cell lines
    • Basic molecular genetics (plasmid preparation)
    • Additional techniques as needed
  • Perform other duties as required

Qualifications

Minimum Qualifications

  • BA/BS in a scientific field required. Must have scientific knowledge in the area of study and basic laboratory skills.
  • Experience working in a research lab
  • Exceptional organizational skills
  • Proficient in using Microsoft Office Suite
  • Independent research experience in addition to school lab experience is usually necessary.

Preferred Qualifications

  • Experience working with mice is strongly desired.
  • Experience using GraphPad Prism and Adobe Illustrator
  • Knowledge or experience maintaining and ordering materials is preferred, in addition to excellent record-keeping skills

What can we provide to you?

  • Direct mentorship from Dr. Termini and other ab members to help you achieve your career goals.
  • Scientific training to broaden your technical and professional skillsets.
  • The opportunity to learn from researchers from unique scientific backgrounds in a team atmosphere.
  • A diverse and inclusive learning environment that supports personal and professional growth.

Fred Hutchinson Cancer Center has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations. As a condition of employment, newly hired employees must, prior to their first day of employment:
Provide proof of being fully vaccinated against COVID-19 ; OR
Initiate the accommodations process to request a religious or medical accommodation (medical accommodations require a healthcare provider’s certification).

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.


The hourly pay range for this position is from $21.56 to $30.69 and pay offered will be based on experience and qualifications.   

 

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).  

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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