Research Lab Manager - HIV Vaccine Trials Network (McElrath Lab)

Job ID
23340
Type
Regular Full-Time
Location
US-WA-Seattle
Category
Laboratory Research Sciences

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from the diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems.  Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.    

 

Fred Hutch offers a vibrant intellectual environment within a beautiful lakeside campus in Seattle’s South Lake Union biotech hub.  The Fred Hutch campus contains five major research buildings along with the Seattle Cancer Care Alliance and is in close proximity to major research partners, such as the University of Washington School of Medicine, Seattle Children’s Research Institute and the Allen Institute for Immunology.

 


 

We have an exciting opportunity for a Laboratory Manager with the McElrath laboratory and the HIV Vaccine Trials Network (HVTN).  The position is for a Laboratory Manager to supervise the HVTN B cell endpoints and exploratory studies group (BEES). In this role, the Laboratory Manager will participate in studies of human B cell immunity to evaluate responses to candidate vaccines. The laboratory’s focus is on clinical trials of HIV and SARS-CoV-2 vaccines as well as investigations of immune responses to HIV and SARS-COV-2 (COVID-19) infections. The Laboratory Manager will conduct laboratory studies, supervise and train research technicians, and implement laboratory quality assurance processes to maintain compliance with Good Clinical Laboratory Practices (GCLP). 

Responsibilities

Reporting to a HVTN Laboratory Staff Scientist, the Lab Manager will lead, mentor, and train a team, design and carry out experiments, and review and analyze data in support of laboratory goals.

 

JOB DUTIES 

 

1. Manage the HVTN BEES laboratory technicians.

  • Supervise, train, and mentor research technicians and students, fostering a positive, collaborative work environment.
  • Lead immune assays, primarily focused on B cell responses to HIV and SARS-CoV-2 investigational vaccines and infection: primarily high parameter flow cytometry and cell sorting; other related assays as needed.
  • Oversee the analysis of flow cytometry data and results.
  • Coordinate with other management staff for the daily operation of the laboratory.
  • Prepare progress reports and documents in support of studies.
     

2. Maintain equipment and implement novel techniques related to flow cytometry.

  • Oversight of the HVTN cell sorters.
  • Development of novel flow cytometry-based panels and assays.
  • Responsible for the design and implementation of major projects and assays related to the research goals of the laboratory.
     

3. Interface with collaborating researchers.

  • Maintain communication with others in the scientific community regarding issues related to both the general project area and the specific research project.
  • Stay abreast of the relevant literature.
  • Write and edit methods and/or results for reports, publications or presentation.
  • Coordinate with statistical groups and internal and external stakeholders.
     

Qualifications

  • Senior position requiring a minimum of a BA/BS in related field, graduate degree preferred; three to five years' progressive experience in a research laboratory setting, or related.  Two to three years of laboratory management experience.  
  • Substantial experience with multi-parameter flow cytometry analysis, assay development and standardization is required.
  • Experience with GCLP/GLP is desirable, as well as a high level of attention to detail, organizational skills, and a commitment to accuracy.
  • Excellent communication (written and oral) and problem-solving skills.
  • Ability to work in a team-oriented research environment in conjunction with a background of collaborative leadership and supervisory duties.
  • Proficiency in the following computer programs is necessary: MS Office, Illustrator or other drawing program, Graph Pad Prism or JMP, and FlowJo.

In addition to job duties at Fred Hutch, this position also requires access to Seattle Cancer Care Alliance, which requires COVID-19 vaccination without exceptions.
Accordingly, as a condition of employment for this Fred Hutch position, newly hired employees must provide proof of vaccination before their first day of employment.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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