Staff Scientist

Job ID
23200
Type
Regular Full-Time
Location
US-WA-Seattle
Category
Staff Scientist

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures for the world’s deadliest diseases and make life beyond cancer a reality. 

  

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.    

  

The Nabet laboratory is seeking a highly motivated, organized, and communicative Staff Scientist. The goals of our research program are to develop strategies to target cancer drivers by controlling protein homeostasis to gain new biological insights into clinically relevant targets and to advance new therapeutic strategies in cancer. The Nabet laboratory develops and deploys innovative chemical biology technologies such as the dTAG system to rapidly eliminate target proteins for therapeutic target discovery and validation (Nabet et al., Nature Chemical Biology 2018; Nabet et al., Nature Communications 2020). The Nabet laboratory is highly collaborative and works extensively with medicinal chemists to develop inhibitors and degraders for cancer drug targets (Ferguson and Nabet et al., Nature Chemical Biology 2020; Li et al., European Journal of Medicinal Chemistry 2022). We are committed to supporting the next-generation of scientists and believe in collaborative science (Nabet, ChemBioChem 2021). This is an exceptional opportunity to join a new team that is pushing the boundaries of cancer chemical biology.

 

Fred Hutch offers great benefits and highly competitive salaries commensurate with experience. 

Responsibilities

We are seeking candidates to contribute to both conceptual and technical aspects of projects in the Nabet laboratory with the ability to drive work independently and as part of a dynamic team. The candidate will develop engineered cancer model systems, advance innovative technologies, and evaluate small molecules in cancer models. The candidate will be involved in mentoring junior trainees and with all the steps of research being completed by the group. The candidate will be expected to contribute to grant writing, present their research during meetings, and be involved in the publishing of scientific abstracts and papers. The candidate will also coordinate collaborations between the Nabet laboratory and researchers in academia and industry worldwide.  

 

To be successful in this position, one must have the ability to communicate effectively with coworkers, working together in executing tasks that engage multiple complementary activities in parallel. In addition to benchwork, these activities include the ability and willingness to take initiative in problem solving and suggestions for workflow improvements will be a key to advancement and associated benefits.  

Qualifications

  • The successful candidate must have a PhD and extensive experience in chemical biology, cancer biology, molecular biology, and/or genetics.  
  • Outstanding technical and communication skills are essential for this position. 
  • A track record of first author publications is highly desirable. 
     

Key knowledge, skills, and experience include: 

  • Highly motivated, organized, communicative, and intellectually curious. 
  • Demonstrated experience in chemical biology, cell and molecular biology, and/or cancer biology. 
  • Cell and molecular biology techniques including western blotting, immunoprecipitation, cloning, PCR, qPCR, sterile tissue culture, virus preparation, DNA/RNA isolation, CRISPR/Cas9-mediated genome editing, flow cytometry, and cell sorting. 
  • Murine modeling work including animal handling, compound administration, and dissection is preferred. 
  • Biostatistics and basic programing skills is preferred. 
  • Use computers, computer-interfaced equipment, robotics, or high-technology applications to perform work duties as well as equipment that requires setup, calibration, maintenance, and troubleshooting. 
  • Analyze and interpret experimental data and summarize findings for presentations, grants, pre-prints, and publications. 
  • Dynamic and driven – engaging and encouraging in team environments 
  • Desire to mentor and train junior trainees including high school students, undergraduates, research technicians, graduate students, and postdoctoral fellows. 
  • Willingness to write and apply for funding opportunities and co-author manuscripts 
  • Provide intellectual and interactive commitment to the position by keeping up with appropriate literature and research publications. 
     

Application Instructions: 

Please apply by submitting your CV, a brief statement of relevant research experience summarizing your interests and experience, and the names and contact information of three references. 

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations. 
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment. 

  

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists. 

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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