Bioinformatician II

Job ID
Regular Full-Time
Fred Hutchinson Cancer Research Center
Biostatistics, Bioinformatics and Computational Biology


Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures for the world’s deadliest diseases and make life beyond cancer a reality.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Bioinformatician II provides specialized consulting and data analysis services to researchers at the Fred Hutch and across the wider Fred Hutch/UW Cancer Consortium. This position requires the ability to work independently, manage multiple overlapping data analysis projects, and communicate effectively with faculty, post-doctoral fellows, and research staff on a wide range of topics in biology, analysis of next-generation sequencing data, sound experimental design, and data science.


The Bioinformatician II reports to the Associate Director of the Bioinformatics Shared Resource and will work with Fred Hutch scientists to refine computational research questions, develop analytical processes applied to large genomic datasets, and provide timely results and documentation for processes used.


Job Duties

  • Perform quality control and end-to-end analysis of large sequence datasets from diverse workflows
  • Consult with researchers to refine research questions and to develop sound experimental designs
  • Identify best-practice bioinformatics tools and strategies to meet the needs of proposed projects
  • Provide figures and written sections describing methods and results for manuscripts, presentations, and grant applications
  • Partner with researchers who are developing novel assays to design appropriate processing and analysis workflows
  • Collaborate with colleagues in the Genomics Shared Resource and the Hutch Data Core to ensure the integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines, and provide training and support as users analyze and interpret results


  • MS or PhD in bioinformatics, computational biology, genetics, or related field
  • At least three years’ professional experience with computational analysis of complex sequence-based data sets including some of these assays: whole exome sequencing; targeted amplicon sequencing; somatic variant calling; bulk RNA-seq expression ; single-cell expression and immune repertoire profiling; CUT&RUN; ChIP-seq; ATAC-seq; or CRISPR/Cas9 knockout screens
  • Demonstrated fluency in R or Python 3, ideally both
  • Proficiency with Linux/Unix shell scripting (e.g., bash)
  • Strong organizational skills, including the ability to manage and prioritize multiple competing tasks
  • Excellent written and verbal communication skills

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at or by calling 206-667-4700.


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