Research Technician I - II

Job ID
22497
Type
Regular Full-Time
Location
US-WA-Seattle
Category
Laboratory Research Sciences

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures for the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


The Brent lab is seeking a Research Technician I-II to support our research in the causes and consequences of non-genetic phenotypic variation.

 

The project specifically includes design and construction of "controllers", complex artificial systems allowing tunable variation-suppressed suppressed expression of genes in mammalian cells.  The Research Technician II will also be involved in efforts to develop Augmented Reality (AR) methods and protocols to aid the controller project, and to in work to learn how to use AR to enable other researchers to better carry out a variety of fundamental experimental manipulations.

 

For this position, we are hoping to find an extraordinary and dedicated individual.  The lab is a multidisciplinary environment and offers a number of intellectual growth paths by which scientists willing to engage can continue to develop scientifically.  Initial funding for this position is for one year but position would be maintained if funding permits.

Responsibilities

This position might call for research activities that include but are not limited to:

  • Generation of variation-suppressed expression constructs to control genes in mammalian cells.
  • Generation and testing of large numbers of intermediate constructs carrying out subfunctions, en route to assembly and testing of the best expression controllers.
  • Facile of contemporary DNA assembly methods including in vitro assembly and relevant construction methodologies in Saccharomyces cerevisiae.
  • Use of software to plan DNA constructions and ability to quickly use lab and other image cytometric software to quantify gene expression in single mammalian cells.
  • Use of flow cytometry and flow cytometric methods.
  • Updating of standard molecular cell biology/genetic techniques, including retroviral and lentiviral gene transduction, CRISPR, and next gen sequencing analysis, as methods change, based on input from other scientists, literature.
  • Engagement with rapidly developing AR and ancillary technologies to aid research projects, willingness to participate in developmental work that will enable others to benefit from this new medium, and possible help with translation to AR representations.
  • Aid with conventional training of laboratory staff and students.
  • Development and updating of laboratory procedures, practice in presentation of data at lab meetings as warranted.
  • Participation in local and national scientific meetings as warranted.

Qualifications

  • Research Technician I
    • BS or BA degree or higher in Biochemistry, Genetics, Cell Biology.
    • A background in molecular biology, DNA work, and mammalian cell culture.
  • Research Technician II
    • Intermediate level position requires a BS or BA degree or higher in Biochemistry, Genetics, Cell Biology.
    • A minimum of 2 years previous experience working in a laboratory.
    • A background in molecular biology, DNA work, and mammalian cell culture.
    • Demonstrated facility with contemporary DNA assembly methods.

 

Strong candidates should have experience with genetics in a prokaryotic system, or in the model systems S. cerevisiae, C. elegans, or D. melanogaster. Relevant research experience with some combination of genetics, molecular biology, single cell assays, DNA/genomic based analytical methods, and cell culture.

 

To APPLY please submit your application with the following:

  • Statement of current work and research interest (up to 1 page).
  • Curriculum Vitae.
  • Names and email addresses of three references that can speak of your research abilities.

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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