Bioinformatician I

Job ID
19821
Type
Regular Full-Time
Company
Fred Hutchinson Cancer Research Center
Location
US-WA-Seattle
Category
Biostatistics, Bioinformatics and Computational Biology

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


We have an opening for a Bioinformatician I in the Bedford lab to work on genomic epidemiology and evolutionary analysis of pathogens including SARS-CoV-2, influenza and Ebola virus. This position will contribute to ongoing work on two major projects: Nextstrain and Seattle Flu Study.

 

Nextstrain is an award-winning tool for tracking infectious disease epidemics developed in collaboration with the Neher lab at the University of Basel. Nextstrain won the Open Science Prize in Feb 2017 and has been instrumental in analysis of the SARS-CoV-2 pandemic, Ebola outbreaks, Zika spread in the Americas and is used by the World Health Organization to aid in the process of influenza vaccine strain selection.

The Seattle Flu Study is a collaboration of groups at the Brotman Baty Institute, the Fred Hutch, the University of Washington, and Seattle Children’s. Already in its third year, this study has produced high-resolution analyses of the spread of SARS-CoV-2 and influenza in Seattle by building a software platform that processes subject and sample metadata, lab assay results, and raw and processed genome data in near-real time.

Responsibilities

The role involves both development and maintenance of bioinformatic analyses and pipelines which underpin both projects’ research aims. This will involve a mixture of independent work, collaboration with scientists in the group and interactions with the wider community. The vast majority of code is open-source. Specific examples from Nextstrain include analytic pipelines that clean and ingest genome metadata, construct consensus genomes, and build phylogenetic trees, as well as tools to enable a diverse range of collaborators to run SARS-CoV-2 analyses through Nextstrain.

 

Work on Seattle Flu Study focuses on pipelines to assemble raw sequence data into consensus SARS-CoV-2 and influenza genomes and deposition of these consensus genomes to public databases.

Interfacing with project collaborators in-person and online is a key aspect of this position. The bioinformatician will work within a small team of existing members of the Bedford lab and the larger research group of the Seattle Flu Study. The Nextstrain team communicates openly about project and organizational decisions and encourages participation by all team members in the decision-making process.

Qualifications

MINIMUM QUALIFICATIONS:

  • Proficient in at least one high-level programming language, such as Python, R, Ruby, JavaScript or Perl
  • Knowledge of molecular biology
  • Knowledge of Biostatistics, Bioinformatics or Computational Biology
  • Knowledge of working in a lab environment
  • Motivated to learn new skills and technologies
  • Execellent written and verbal communication skills

PREFERRED QUALIFICATIONS:

  • Expertise in genomics
  • Experience writing biostatistic analysis programs with biological decisions
  • BS degree in a Biology discipline
  • Experience with pipeline or workflow automation
  • Familiarity with software development best practices
  • Experience configuring and deploying analyses on a cloud infrastructure
  • Experience and willingness to participate in team decision-making processes

To be considered for this position:

  • Candidates must provide a coding sample by submitting it with their application.
  • The hiring team will review any programming language you choose.
  • Please provide either a zipped up project included as an "additional attachment" OR,
  • Please provide a link to a specific repo online by attaching a short statement pointing to the URL of this repo as an "additional attachment" to your application.
  • Please name this zip archive / file as "last name_job ID_coding sample".
  • If you don't have code that can be publicly shared, please notate this in your application. 

 

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment. 

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

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