Research Technician II-III, Pancreas Cancer Research

Job ID
19377
Type
Regular Full-Time
Company
Fred Hutchinson Cancer Research Center
Location
US-WA-Seattle
Category
Laboratory Research Sciences

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


 

The Hingorani Laboratory investigates molecular and cellular mechanisms of pancreatic ductal adenocarcinoma (PDA) pathogenesis. The murine models of distinct genetic subtypes of pancreas cancer that we have developed form the basis of our integrated, systematic, and multidisciplinary research program. Our efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures, activated fibroblasts, and multiple mechanisms of immune suppression); identifying and disrupting molecular drivers of metastasis; and developing immune-based treatment strategies. Our ultimate aim is to take our discoveries and reduce them to practice in the clinic in order to radically transform the approach and prognosis for patients with this devastating disease.


This Research Technician II/III position represents an excellent opportunity for an experienced, highly motivated individual with a passion for science to work and learn in a dynamic scientific environment while addressing important problems relevant for the successful treatment of cancer.

Responsibilities

The research technician will be involved in all aspects of murine preclinical studies including but not limited to breeding, genotyping, ultrasound and other imaging techniques, drug treatments, and performing necropsies to obtain tissues for histology and cell lines. The technician may be involved in derivation, maintenance and study of primary cell lines; isolation of DNA, RNA, and proteins; as well as other techniques such as FACS sorting and expanding cells in vitro, analyzing cell phenotype and function using techniques including flow cytometry, proliferation assays, cytotoxicity assays, PCR, RT-PCR, sequencing, and ELISpot. Molecular techniques used in the lab include cloning, transfection/transduction of cell lines, gene targeting and northern and Southern blotting. Biochemical and cellular techniques include SDS-PAGE, western blotting, immunofluorescence, and immunohistochemistry. The technician may assist in the design, analyses and reporting of team and independent experiments. The technician will also assist with the management and organization of a fast-paced lab and perform other duties as assigned by supervisor.

Qualifications

  • Research Technician II: Intermediate level position requiring a minimum of 2 years previous experience working in a laboratory and BA/BS in bioengineering, biophysics or a biological science. Independent research experience outside of laboratory course work is necessary.
  • Research Technician III: Advanced position requiring a minimum of 4 years prior experience in a laboratory setting performing experiments with a high degree of independence and a BA/BS in in bioengineering, biophysics or a biological science
  • Laboratory research experience including small animal surgeries and injections, cell tissue culture, flow cytometry, and molecular biology techniques are required
  • Computer skills: Microsoft Excel, Prism (Graphpad), FlowJo, and statistical programs for data analysis
  • Excellent organizational and interpersonal skills are required
  • Strong troubleshooting skills and the ability to multi-task with precise attention to detail is especially critical
  • Experience with genetically engineered murine models of pancreas cancer or other solid tumors is desired

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at hrops@fredhutch.org or by calling 206-667-4700.

Options

Sorry the Share function is not working properly at this moment. Please refresh the page and try again later.
Share on your newsfeed