Project Manager III - HVTN B Cell

Job ID
Regular Full-Time
Fred Hutchinson Cancer Research Center
Laboratory Research Sciences


Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


The HIV Vaccine Trials Network (HVTN) Laboratory Center in the Immunology & Vaccine Development Program of the Vaccine & Infectious Disease Division is dedicated to understanding human immunity and mechanisms of vaccine-induced immune protection against HIV and SARS-CoV-2.


This position will be with the McElrath HVTN Laboratory. The Research Project Manager will lead detailed evaluation of B cell immune responses to candidate HIV and SARS-CoV-2 vaccines in clinical trials as well as investigations of immune responses to HIV and SARS-CoV-2 (COVID-19) infections. This individual will develop and implement novel methods, train and supervise technicians, design experiments and oversee collection and analysis of data.


Reporting to the HVTN Laboratory Associate Director, the Research Project Manager will coordinate and carry out activities including but not limited to:

  • Lead, develop and conduct immune assays to assess antigen-specific B cell responses: high-dimensional multiparameter flow cytometry, FACS sorting, isolation and culturing of antigen-specific primary B cells, biochemical assays (protein gels, western blots and ELISAs), BCR sequencing and other assays as relevant.
  • Supervise, mentor, and train a team of research technicians to conduct B cell immune assays
  • Analyze flow data and results
  • Coordinate with statistical groups and internal and external stakeholders
  • Participation in both formal and informal sharing of data amongst collaborating researchers
  • Assist with external progress reports, grant applications and scientific articles
  • Coordinate establishment of new techniques in the laboratory
  • Other duties and projects as assigned


  • Advanced degree preferred; BA/BS with 10+ years work experience or equivalent combination of relevant work experience and post-bachelor’s education required.
  • Experience with human B cell immunology and multiparameter flow cytometry and analysis is required
  • Excellent communication (oral and written) and problem-solving skills are required
  • Duties will require working in a team-oriented research environment and in serving in a collaborative and supervisory capacity
  • A strong background in collaborative team leadership, positive communication and project completion is preferred
  • Motivation and adaptability are essential, as is a keen interest in the HIV vaccine field
  • Knowledge of human clinical trials and/or GCLP/GLP experience is required
  • Proficiency in the following computer programs is necessary: MS Office, Illustrator or other drawing program, Prism, JMP, Excel, R and/or SAS statistical analysis program, and FlowJo and/or other flow data analysis programs.
  • Hours: Must be flexible, able to work some nights and weekends
  • Special qualifications: willingness to work with biohazardous (e.g., HIV-1) materials, required

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at or by calling 206-667-4700.


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