Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.
A fully-funded post-doctoral research fellow position is available in the Hatch Lab in the Basic Sciences Division. We study the structure and dynamics of the mammalian nuclear envelope, and our primary interests are to understand why and how nuclear membranes rupture and repair, and how defects in nuclear membrane stability impact cancer development (Hatch et al., Cell, 2013; Maciejowski and Hatch, Ann Rev Cell Dev Biol, 2020; Young, Gunn, and Hatch, MBoC, 2020). The Hatch lab uses a variety of techniques to achieve these goals with a focus on microscopy and cell-based tool development.
The fellow will be responsible for developing, in discussion with Dr. Hatch, and executing a project related to the core interests of the lab with the goal of developing a new line of inquiry that the fellow could start their own research program with, if desired.
Current areas of interest are: identifying proteins that drive membrane repair and how membrane gap size influences repair pathway choice, determining why chromatin state regulates nuclear lamina organization and membrane stability in micronuclei, developing new tools to track and isolate micronucleated chromatin and cells, and designing new experimental models to investigate how chromosome missegregation into micronuclei impacts cell transformation and tumor progression. The development of collaborative projects with other labs at Fred Hutch or elsewhere is of substantial interest.
Strong candidates will have demonstrated excellent abilities to independently design and execute a project, identify and communicate with scientists outside their lab to learn new techniques or topics, and effectively communicate the significance of their research in both oral and written presentations.
To apply to this position please provide the following: