Research Technician I: Immunotherapy/T Cell Engineering and Imaging

Job ID
Regular Full-Time
Fred Hutchinson Cancer Research Center
Laboratory Research Sciences


Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


A research technician position (full-time) is available immediately in a laboratory within Fred Hutchinson Cancer Research Center’s Translational Research Program. The Laboratory for the Study of Metastatic Microenvironments focuses on understanding the biology underlying disseminated tumor cell (DTC) dormancy and formulating therapeutic means to eradicate dormant DTCs. We are looking for a dynamic, bright, meticulous, and highly motivated individual to join our team and to help us understand how DTCs and engineered immune cells interact.


The ideal candidate will have a strong interest in immunology, engineering T cells, and imaging. They will be responsible for performing standard and investigative laboratory work, including: following detailed, time-sensitive multi-day protocols for engineering immune cells, assisting with adoptive transfer experiments to apply engineered cells to an in vivo setting, and quantifying outcomes through a variety of means, including static imaging of tissue sections and dynamic imaging of live tissues.    


This position will work under the Principal Investigator and work with two talented postdoctoral fellows in the lab. The individual will use discretion and judgment in carrying out the following job duties.

  • Meticulous adherence to detailed protocols to generate engineered T cells targeting specific tumor antigens and neo-antigens
  • Perform standard assays to quality control each batch prep of engineered immune cells
  • Assist with live animal studies to measure the efficacy of engineered T cells against dormant DTCs and proliferative micrometastases in live and in static tissues.
  • Prepare and monitor animals during experiments
  • Breed a number of transgenic strains, genotype offspring and take careful note of resulting genotypes/phenotypes
  • Perform statistical analyses to analyze resulting data
  • Perform other duties as required


A bachelor’s degree in bioengineering, biophysics or biological sciences and at least one-year experience in basic laboratory skills is required. Experience with mammalian cell culture -or- laboratory murine handling is required. Independent research experience outside of laboratory course work is strongly desired. The ideal candidate will be meticulous, self-driven, enthusiastic, well-organized, and excited to learn and conduct new surgical techniques.

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