Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Kugel Laboratory is seeking highly motivated postdoctoral fellows interested in exploring how the dysregulation of chromatin modifying enzymes and developmental pathways contribute to pancreatic cancer pathogenesis and, further, whether these pathways present liabilities that can be exploited for cancer therapy.
Successful candidates will learn to generate and exploit a series of cancer model systems including genetically engineered murine models (GEMMs), patient-derived xenografts and novel human cancer cell lines to understand fundamental pathogenic mechanisms underlying pancreatic cancer. To answer these questions the laboratory uses state-of-the-art techniques in murine models and genetics, molecular biology, cell biology, biochemistry, metabolism, RNA profiling, proteomics, pharmacology, genomics and computational biology.
Qualified applicants will have recently obtained a PhD and/or MD, or be nearing completion of their graduate studies and have an interest in cancer research. A track record of productive research is strongly preferred. Applicants with specific expertise in RNA biology, biochemistry, cell biology, cancer genomics, murine models or computational biology are highly encouraged to apply. Excellent verbal and written communication skills are required. Fellowship opportunities are available through several philanthropic and government organizations; and recruits who join the lab will be supported in their applications.
Please apply by submitting a CV, a brief description of past research experiences and future goals (not more than 1-2 pages) and contact information for three references.