Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
Our laboratory focuses on how gene regulation, chromatin structure, and nuclear organization are linked, with a special emphasis on changes that occur with differentiation. This is a part-time position where effort is negotiable depending on the candidates’ skills and needs. The person in this position will be the lead on a collaborative project to define all cis-acting regulatory sequences on a genome-wide basis. The focus of this work is the isolation of defined populations of hematopoietic cells at defined stages of development and differentiation with the goal of subjecting them to a variety of molecular analyses. Samples will be obtained from wildtype and mutant mice, at baseline, and while recovering from stress. The candidate will prepare samples for analysis by Next Generation Sequencing (NGS). This work will require managing a mouse colony as well as isolating and analyzing mouse tissues.
The research technician will work under the direct supervision by the principal investigators and be working with outside collaborators. This individual will be the sole Fred Hutch person doing bench work on this project and will need to work semi-independently and be adept at balancing responsibilities. To be successful in this laboratory the technician will need to work fairly autonomously and take the lead on trouble-shooting. Excellent communication, documentation and organization skills are essential.
Comfort, and being facile with flow cytometry, including optimizing antibody staining and data analysis. Having job experience with this would be a major benefit.
Comfort with basic mouse husbandry, genotyping and isolation of organs. Having job experience with this would be a major benefit.
Tissue culture experience.