• Staff Scientist, Bernstein Lab

    Job ID
    14735
    Type
    Regular Full-Time
    Company
    Fred Hutchinson Cancer Research Center
    Location
    US-WA-Seattle
    Category
    Laboratory Research Sciences
  • Overview

    Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

    Responsibilities

    The Bernstein Lab is recruiting a staff scientist to engage in studies of the role of the Notch pathway in normal and malignant hematopoiesis and in T cell development.

     

    The research in the Bernstein lab has primarily focused on developmental aspects of normal and leukemic hematopoiesis with the specific goal of developing novel therapeutic modalities. In these efforts we have identified maturation linked cell surface antigens and have utilized this information for developing methods for targeted therapy of hematologic malignancies and for isolating and characterizing normal and malignant human hematopoietic stem cells. Current studies of normal hematopoiesis are aimed at determining the role of the Notch pathway to direct primitive hematopoietic precursors to commit to a particular maturational pathway or to self-renew. These efforts are currently being extended in studies of CAR T-cell self renewal and differentiation. Recent studies of leukemia focus on how cells in the marrow microenvironment protect the leukemic stem cells from therapy.

    Qualifications

    Required:

    • Ph.D. degree in immunology, cellular and molecular biology, or a closely-related field.
    • Significant experience with flow cytometry essential as is a strong background in stem cell biology or cellular immunonology.
    • Three years of postdoctoral training/research experience.

    Preferred:

    • Five years of postdoctoral training/research experience.

    Our Commitment to Diversity

    We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

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