• Research Technician II: Cancer Immunology and Immunotherapy

    Job ID
    14561
    Type
    Regular Full-Time
    Company
    Fred Hutchinson Cancer Research Center
    Location
    US-WA-Seattle
    Category
    Laboratory Research Sciences
  • Overview

    Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


    A research technician position (full-time) is immediately available in the Barry laboratory within the Fred Hutchinson Cancer Research Center’s Translational Research Program. The Barry lab focuses on understanding how the immune system responds to cancer and can be manipulated to target cancer. Our studies utilize human immunology, murine models of cancer, state-of-the-art imaging techniques, RNA sequencing techniques, and immunological techniques to explore the role of the innate immune system in controlling immune responses to cancer. Our goal is to understand the basic mechanisms regulating the immune response to cancer in order to target these pathways in patients, ultimately leading to increased response rates of current FDA-approved immunotherapy drugs and identification of novel pathways that can be targeted to increase immune responses to cancer.


    We are looking for an ambitious, highly organized, and highly motivated individual who will be responsible for performing an independent investigative project while also undertaking standard laboratory work in support of scientific research. In both roles this individual will work with human tumor samples, murine models, conduct cell culture experiments, operate analytical instruments, recover, compile and verify the accuracy of research data, and prepare these data as both written and visual summaries.

    Responsibilities

    This position will work under the Principal Investigator and work with the laboratory personnel. The individual will use discretion and judgment in carrying out their job duties. In addition to being responsible for conducting an independent research project the individual will manage the murine colony and day-to-day lab needs. This is an ideal position for a recent graduate who wants to gain an immersive research experience before pursuing graduate and/or medical school.


    The research technician will primarily carry out an independent research project that involves cancer immunology, human immunology, immunotherapy, cell biology, and molecular biology. Specific duties are:

    • Perform documented protocols and assays
    • Identify methodological problems in research protocols and implement modifications to optimize experimental results
    • Perform experiments at the bench level to support independent investigative work. This will involve cell culture, live cell imaging, immunofluorescent staining, processing tissue for single cell analysis, tissue sectioning, plasmid preparation, cloning, retro- and lenti-virus production, and others as necessary
    • Maintain laboratory records and compile data on experiments and assays
    • Perform basic statistical analysis of experimental results and interpret experimental results
    • Assist in the publication of results by writing, proofreading, editing, and contributing ideas


    The research technician will participate in lab meetings and journal clubs. Specific duties are:

    • Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data in one-on-one meetings with the principal investigator, lab meetings, and occasionally larger campus group meetings
    • Read and discuss scientific articles to inform ideas and directions for research projects in the lab


    Other responsibilities include general lab maintenance and other duties as needed. Specific duties are:

    • Manage a murine colony, including breeding, genotyping, and weaning litters, as well as techniques associated with mouse tumor experiments
    • Prepare and maintain laboratory reagents, stocks, cultures or cell lines
    • Operate and carry out basic maintenance of laboratory equipment
    • Order and maintain appropriate levels of supplies
    • Assist and/or lead in the processing of human and murine tissue for imaging, multiparamter flow-cytometric analysis, and RNA sequencing

    Qualifications

    Required:

    • A bachelor’s degree in the biological sciences
    • Significant laboratory bench research experience outside of course work
    • The candidate must have an interest in immunology and immunotherapy
    • Reliability is essential
    • Good interpersonal skills
    • Good verbal and written communication skills

    To be successful in this position, the technician must be ambitious, have scientific curiosity, a high level of self-motivation, the ability to take instruction and correction, good organizational skills, the ability to work and think independently, and wants to stay at least two years

     

    Preferred experience (not required):

    • Murine models
    • Molecular biology
    • Mammalian cell culture
    • Flow cytometry
    • Tumor biology, and/or immunology

    Our Commitment to Diversity

    We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

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