• Research Technician II: Tumor Immunology

    Job ID
    14499
    Type
    Regular Full-Time
    Company
    Fred Hutchinson Cancer Research Center
    Location
    US-WA-Seattle
    Category
    Laboratory Research Sciences
  • Overview

    Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


    A research technician position (full-time) is immediately available in an established laboratory within Fred Hutchinson Cancer Research Center’s Translational Research Program. The Laboratory for the Study of Metastatic Microenvironments, directed by Cyrus Ghajar, focuses on understanding the biology underlying disseminated tumor cell (DTC) dormancy and formulating therapeutic means to eradicate dormant DTCs.


    We are looking for a dynamic, organized, and highly motivated individual who will be responsible for performing standard and investigative laboratory work in support of research seeking to leverage immunology to target dormant DTCs in order to prevent metastasis. This will entail working with murine models, conducting cell culture experiments, operating analytical instruments, recovering, compiling and verifying the accuracy of research data; and preparing these data as both written and visual summaries.

    Responsibilities

    This position will work under the Principal Investigator and work with the laboratory personnel. The individual will use discretion and judgment in carrying out the following job duties:

    • Manage a murine colony, including breeding, genotyping, and weaning litters, as well as live imaging and techniques associated with tumor xenograft experiments.
    • Perform experiments at the bench level to support investigative work. This will involve two- and three-dimensional cell culture, live cell imaging, immunofluorescent staining, tissue sectioning, plasmid preparation, cloning, retro- and lenti-virus production, and immunoblotting.
    • Prepare and maintain laboratory reagents, stocks, cultures or cell lines.
    • Learn and conduct cutting edge assays to assess T cell specificity and function.
    • Perform and modify documented protocols and assays.
    • Maintain laboratory records and compile data on experiments and assays.
    • Interpret and report experimental results.
    • Perform statistical analysis of test results and prepare written reports on work performed.
    • Operate and carry out basic maintenance of laboratory equipment.
    • Order and maintain appropriate levels of supplies.
    • Identify methodological problems in research protocol and implement modifications to optimize experimental results.
    • Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data.
    • Assist in publication of results by proofreading, editing, and contributing ideas.
    • May perform statistical analyses, write computer programs, or manage research database.
    • Perform other duties as required.

    Qualifications

    • A bachelor’s degree in the biological sciences and at least two years experience in basic laboratory skills are required, including experience with murine models and cell culture
    • Independent research experience outside of laboratory course work is strongly desired, as is a background in tumor biology and/or immunology.
    • The ideal candidate will be well-organized, pay exquisite attention to detail, have some experience in pre-clinical models, skilled in collecting and analyzing data (e.g., SigmaPlot), and adept in establishing and managing lab databases (Google Sheets, MS Excel).

    Our Commitment to Diversity

    We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

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