Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Newell Lab (publication list)was originally established in 2012 at the Singapore Immunology Network, Singapore and then moved to the Vaccine and Infectious Disease Division of the Fred Hutchinson Cancer Research Center in August 2018.
A major goal of lab is to exploit T cell antigen-specificity to gain clinically relevant insights about human immunity in the context of cancer and infectious disease. This is achieved through leveraging expertise in the use of highly-multiplexed peptide-MHC tetramer staining in conjunction with mass cytometry or single-cell sequencing to deeply profile human antigen-specific T cells. In addition, novel experimental and computational approaches are being developed that allow for improved examination of T cell phenotypes, function, antigen specificity, as well as T cell receptor repertoire. Although the lab focuses mostly on studying the roles of T cells in human health and disease, we also participate in many projects related to other cell types and mouse tumor systems are also employed.
Our Lab is seeking outstanding and open-minded Postdoctoral Fellows to work on developing and implementing cutting edge analysis to investigate the roles of T cells in various models of cancer and infectious disease.