• Post-Doctoral Research Fellow, Protein Chemist/Analytical Chemist

    Job ID
    Regular Full-Time
    Fred Hutchinson Cancer Research Center
    Post-Doctoral Research Fellows and Associates
  • Overview

    Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


    The Paulovich Lab at Fred Hutch is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine (patient selection and identification of novel therapeutic targets). The lab has a major focus on mass spectrometry, especially multiple reaction monitoring. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.


    This is a terrific opportunity for a highly motivated, interactive, Protein or Analytical Chemist to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing proteomic experiments and participating in the analysis and interpretation of results.


    • Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)

    • Perform HPLC separations and maintain HPLC instruments

    • Work with antibodies (immunoaffinity purification, immobilization on solid supports, screening hybridomas for mass spectrometry)

    • Generate mass spectrometry (MS)-based proteomics data and maintain MS instruments

    • Contribute to the analysis of proteomic (mass spectrometry) datasets

    • Collaborate effectively with an interdisciplinary team spanning expertise in biology, analytical chemistry, and statistics

    • Collaborate with others to develop new methods and tools that support research objectives

    • Maintain research results files and databases

    • Assist with written progress reports and development of standard operating protocols (SOP)

    • Assist with writing scientific manuscripts for peer-reviewed journals


    • Ph.D. degree in Protein Chemistry, Analytical Chemistry, Biochemistry, or related discipline is required
    • The work is rigorously quantitative, and exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintaining records are critical
    • The position includes drafting reports and manuscripts for publication, as well as presenting experimental results to the research team and collaborators. Thus, excellent writing and oral communication skills are required
    • Previous experience in a CLIA or clinical lab environment is a plus
    • A demonstrated track record of authorship on peer-reviewed journal publications is a plus

    Our Commitment to Diversity

    We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.


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