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The Hingorani Laboratory in the Clinical Research Division investigates the cellular and molecular mechanisms of pathogenesis of pancreatic ductal adenocarcinoma (PDA) or, more commonly, pancreas cancer. PDA is a nearly uniformly lethal disease that defies all forms of conventional chemo- and radiotherapy. To answer fundamental questions about the biology of PDA we have turned to genetically engineered murine models. By directing the expression of key mutations in specific oncogenes and tumor suppressor genes to the murine pancreas, we have developed models that faithfully mimic the spectrum of human PDA from its earliest preinvasive lesions to locally invasive and widely metastatic disease. Our goals are to use these models to understand fundamental mechanisms of disease pathogenesis and to design and test strategies for early detection and for treatment and chemoprevention. This position represents an excellent opportunity for a highly motivated individual with a passion for science to work and learn in a dynamic scientific environment while addressing important problems relevant for the successful treatment of cancer.
This is a part-time position for up to 20 hours per week.
This technician will work closely with the Research Histotechnologist who runs the laboratory’s dedicated histopathology operations. Primary responsibilities include, but are not limited to, embedding and fixing tissue, cutting tissue sections, and staining slides. The technician will also assist with the general running and organization of the laboratory, including ordering reagents and supplies, maintaining inventories, preparing solutions, stains, and reagents and will operate and maintain all histology area lab equipment.
An associates' degree in histology or a bachelor’s degree in a biological science and a minimum of one year of research experience is required. Experience with histology is required. Strong troubleshooting skills and the ability to multi-task with precise attention to detail is especially critical. Candidate must be detail oriented and able to perform work with accuracy regardless of volume.