• Research Histotechnologist III

    Job ID
    Regular Full-Time
    Fred Hutchinson Cancer Research Center
    Clinical Research Support Services
  • Overview

    Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


    The Experimental Histopathology Shared Resource laboratory is recruiting a research histotechnologist to provide customized histology and immunohistochemistry support for Fred Hutchinson research efforts. The histotech will assist with the design of innovative specimen preparation and staining protocols in a customer service based, team oriented work environment. The histotech will support the lab in all aspects of the operations, including maintaining workflow and lab operations and assist in specimen preparation and equipment maintenance.


    In order to meet coverage requirements in the afternoon and provide excellent service to our investigators, this position will be required to work scheduled hours from 8.30 am to 5pm Monday to Friday.


    • Accurately log-in, label, organize, and track specimens
    • Gross and fix tissue, process and paraffin embed samples; process and freeze samples in OCT
    • Perform high throughput cutting of paraffin and frozen blocks for routine and special stains, immunohistochemistry, in situ hybridization, and molecular studies
    • Perform routine and customized (complex) immunohistochemistry and in situ hybridization, on an automated platform as well as routine (H&E) and special stains histology
    • Assist in the vetting of antibodies to be used for specific applications
    • Assist in establishing, optimizing, and customizing histology procedures for fixing, processing, sectioning, staining, and reagent preparation to support immunohistochemistry other research projects
    • Research, troubleshoot, and test new reagents
    • Optimize antigen retrieval conditions, blocking, detection, and titer to ensure ideal staining conditions for antibodies
    • Inventory, maintain, and order supplies, as necessary
    • Prepare reagents from detailed laboratory procedures and document that quality control standards are being met
    • Act as histology and immunohistochemistry resource for researchers to assist with preparation of their protocols
    • Participate in group meetings with laboratory staff and researchers to discuss experimental design that will meet research goals
    • Assist in the design and writing of laboratory protocols for all procedures
    • Perform routine maintenance on laboratory equipment, including the microtome, cryostat, freezer, tissue processor, and stainers
    • Assist in organizing work and storage space and in general lab maintenance
    • Perform other duties, as assigned


    • Bachelor’s degree with 3-4 years of relevant Histology/Pathology experience and Associate Diploma from a nationally recognized histology program is required
    • HT or HTL (ASCP) certification is required plus one additional certification in immunohistochemistry, molecular pathology, necropsy, digital image analysis or demonstrate mastery of technique
    • Strong troubleshooting and problem-solving skills are required
    • This position requires excellent written and verbal communication skills and the ability to work positively in a customer-oriented environment
    • The successful technologist must be able to work accurately and efficiently, be detail oriented, and work both independently and within a group
    • Advanced knowledge in imaging, microscopy and image analysis for this position is desirable
    • In addition, the incumbent must be flexible and skilled at organizing and prioritizing tasks. Ability to learn new software packages/programs as well as proficiency with Microsoft Word, Excel, SharePoint, and Internet Explorer are required

    Our Commitment to Diversity

    We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.


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