• Research Technician I, Novel Approaches to Study Antigen-Specific T Cells

    Job ID
    Regular Full-Time
    Fred Hutchinson Cancer Research Center
    Laboratory Research Sciences
  • Overview

    Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


    The Newell Lab (originally established in 2012 at the Singapore Immunology Network, Singapore) is now a part of the Vaccine and Infectious Disease Division of the Fred Hutchinson Cancer Research Center. The lab will continue to focus on the application and develop novel approaches for studying antigen-specific T cells in the context of cancer and infectious diseases. In addition to leveraging expertise in the use of highly-multiplexed peptide-MHC tetramer staining in conjunction with mass cytometry to deeply profile antigen-specific T cells, novel experimental and computational approaches will be developed that allow for improved examination of T cell phenotypes, function, antigen specificity, as well as T cell receptor repertoire. Although the lab focuses mostly on studying the roles of T cells in human health and disease, mouse tumor systems are also employed. A major goal of lab is to identify useful biomarkers of clinical outcomes that take advantage of modern experimental and computational approaches with particular focus on human chronic infection and cancer.


    Our Lab is seeking an outstanding technician to work on developing and implementing cutting edge analysis to investigate the roles of T cells in various models of cancer and infectious disease.


    • Learning nuances of implementation of mass cytometry for the analysis of relevant cellular samples
    • Application of highly multiplexed peptide-MHC multimer analysis using mass cytometry
    • Lab management and organization
    • Initiate and carry out scientific projects, under the supervision of Evan Newell


    • BA/BA degree in the sciences
    • Experience with flow cytometry (mass cytometry experience not required)
    • Experience with molecular biology techniques is desired
    • Experience with protein expression and purification would be advantageous
    • Computer programming or bioinformatics skills would also be advantageous
    • Good organization skills
    • An ability to learn new techniques and troubleshoot assays
    • Good team player, independent, self-driven with good interpersonal skills

    Our Commitment to Diversity

    We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.


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