• Research Technician I-II, Molecular Virology

    Job ID
    11601
    Type
    Regular Full-Time
    Company
    Fred Hutchinson Cancer Research Center
    Location
    US-WA-Seattle
    Category
    Laboratory Research Sciences
  • Overview

    Cures Start Here. Fred Hutchinson Cancer Research Center (Fred Hutch), home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Careers Start Here.

     

    A hallmark of many diseases and cancers is the aberrant regulation of chromatin. Much like the cellular genome, viral genomes are compacted in virus particles with small basic molecules to maximize space and be poised for gene expression. Some DNA viruses use cellular histone proteins to compact their genomes whereas others use small basic molecules. The Avgousti lab in the Human Biology Division at Fred Hutch uses a multidisciplinary approach to uncover the mechanisms by which viruses hijack chromatin. Our goal is to advance basic understanding of viral manipulation of chromatin and reveal new aspects of chromatin biology thereby providing new avenues for possible therapeutic advances.

     

    Our current research efforts are divided among studies of (1) a small basic protein from adenovirus, protein VII, that serves to compact its genome while wreaking havoc on the host genome, (2) host histones found on herpesvirus genomes during infection and how they can be exploited to block infection, and (3) using viral tools to block inflammation and cancer progression.

     

    Additional information about research in the Avgousti lab can be found at:

    https://research.fhcrc.org/avgousti/en.html

    Responsibilities

    Research technicians will be responsible for performing standard and investigative laboratory work in support of scientific research by performing bench-level experiments, operating analytical instruments, recovering, compiling and verifying the accuracy of research data; performing calculations; preparing charts, graphs and summaries.

     

    JOB DUTIES

    1. Perform experiments at the bench level to support investigative work.
    2. Prepare and maintain laboratory reagents, stocks, cultures or cell lines.
    3. Perform and modify documented protocols and assays.
    4. Maintain laboratory records and compile data on experiments and assays.
    5. Interpret and report on experimental results.
    6. Perform statistical analysis of test results and prepare written reports on work performed.
    7. Operate and carry out basic maintenance of laboratory equipment.
    8. Order and maintain appropriate levels of supplies.
    9. May supervise work-study students.
    10. Participate in lab meetings and journal clubs.
    11. Perform other duties as required.

    Qualifications

    Tech I: BA/BS in a scientific field required. Must have scientific knowledge in the area of study and basic laboratory skills. Independent research experience in addition to school lab experience is required.

    Tech II: Intermediate level position requiring 2 years previous experience working in a laboratory and BA/BS. A Master's degree can substitute for 2 years of post-graduation lab experience.

     

    A successful candidate will have scientific curiosity, a high level of self-motivation, the ability to take instruction and correction and to follow directions, good organizational skills, the ability to work and think independently and be able to make at least a two year commitment. The candidate have a track record of reliability and good verbal and written communication skills. Must be able to distinguish different intensities and hues of red color. This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate school.

    Our Commitment to Diversity

    We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.

    Options

    Sorry the Share function is not working properly at this moment. Please refresh the page and try again later.
    Share on your newsfeed