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The Silberstein Lab, a newly-established hematopoiesis laboratory led by a physician-scientist is seeking to recruit a research technician who is interested in pursuing laboratory-based research project. The laboratory is located at Fred Hutchinson Cancer Research Center in Seattle.
The main goal of the laboratory is to combine basic stem cell biology and clinically relevant mouse models in order to develop new therapeutic approaches to promote HSC function in bone marrow failure and to enhance hematopoietic reconstitution post-transplant. We are particularly interested in using microenvironment-derived molecules as drugs or therapeutic targets, and have identified several novel niche factors using proximity-based single cell analysis as a discovery strategy (for details, please see Silberstein et al, Cell Stem Cell 2016, Goncalves, Silberstein et al, Cell 2016).
A successful candidate will be able to assist with 1) cell culture, 2) stem cell expansion studies and 3) development of stem cell enrichment protocols. The position may involve additional responsibilities, such as processing of primary tissue samples, and culture/analysis of cells infected with HIV and related viruses. The candidate should be motivated to participate in sample collection and procession from preclinical modeling experiments. This position affords the motivated technician an opportunity to develop/utilize both tissue culture and molecular biology skills.