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A newly-established laboratory in the Division of Human Biology seeks a postdoctoral fellow to engage in laboratory-based science. The major focus of the lab is to understand the biological determinants of aggressive prostate cancer and to exploit inherent molecular vulnerabilities in subtypes of lethal, metastatic prostate cancer. Particular areas of emphasis include characterizing the functional contribution of specific oncogenic events to cancer initiation and progression, disrupting the regulation of androgen receptor (AR) and Myc protein stability, identifying cancer differentiation-specific cell surface antigens, and developing immune-based strategies for precision medicine in prostate cancer.
This is a basic science position that focuses on delineating the molecular mechanisms of advanced prostate cancer with the opportunity for translational studies evaluating the efficacy of novel therapeutics.
Ph.D. degree in molecular biology, cell biology, immunology, genetics or a related field with a track record of high-quality publications is required. Additionally, experience in one of the following areas is required: bioinformatics, biomarker characterization, antibody therapy, adoptive T cell therapy, or analysis of immune cell subsets. Knowledge/exposure in genomics, transcriptomics, proteomics, biobanking, mouse xenograft models, and biostatistics is desired. Expertise in molecular and cellular biology techniques – molecular cloning, cell culture, immunoblotting, immunohistochemistry, flow cytometry, ELISA, cell viability and cytotoxicity assays – is also required. Candidates need to be highly-motivated, organized individuals who think independently but enjoy working as part of a dynamic, collaborative, and multidisciplinary team. Excellent verbal and written communication skills are essential.