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Post-Doctoral Research Fellow, Immuno-Oncology

Post-Doctoral Research Fellow, Immuno-Oncology

Job ID 
11131
Type 
Regular Full-Time
Company 
Fred Hutchinson Cancer Research Center
Location 
US-WA-Seattle
Category 
Post-Doctoral Research Fellows and Associates

More information about this job

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose, and treat cancer and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here

Responsibilities

A newly-established laboratory in the Division of Human Biology seeks a postdoctoral fellow to engage in laboratory-based science. The major focus of the lab is to understand the biological determinants of aggressive prostate cancer and to exploit inherent molecular vulnerabilities in subtypes of lethal, metastatic prostate cancer. Particular areas of emphasis include characterizing the functional contribution of specific oncogenic events to cancer initiation and progression, disrupting the regulation of androgen receptor (AR) and Myc protein stability, identifying cancer differentiation-specific cell surface antigens, and developing immune-based strategies for precision medicine in prostate cancer.

 

This is a basic science position that focuses on delineating the molecular mechanisms of advanced prostate cancer with the opportunity for translational studies evaluating the efficacy of novel therapeutics.

Qualifications

Ph.D. degree in molecular biology, cell biology, immunology, genetics or a related field with a track record of high-quality publications is required. Additionally, experience in one of the following areas is required: bioinformatics, biomarker characterization, antibody therapy, adoptive T cell therapy, or analysis of immune cell subsets. Knowledge/exposure in genomics, transcriptomics, proteomics, biobanking, mouse xenograft models, and biostatistics is desired. Expertise in molecular and cellular biology techniques – molecular cloning, cell culture, immunoblotting, immunohistochemistry, flow cytometry, ELISA, cell viability and cytotoxicity assays – is also required. Candidates need to be highly-motivated, organized individuals who think independently but enjoy working as part of a dynamic, collaborative, and multidisciplinary team. Excellent verbal and written communication skills are essential.

Our Commitment to Diversity

We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We are proud to be an Equal Opportunity and VEVRAA Employer. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability, marital or veteran status, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to our Employee Services Center at escmail@fredhutch.org or by calling 206-667-4700.