Cures Start Here. Fred Hutchinson Cancer Research Center (Fred Hutch), home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Careers Start Here.
The Gujral Lab (http://research.fhcrc.org/gujral) at the Fred Hutchinson Cancer Research Center has an opening for a postdoctoral fellow. Our lab combines approaches from molecular genetics with cell and systems biology to study the interactions between tumor cells and host cells in the tumor microenvironment.
Although progress has been made in the past several decades in understanding and developing treatments for cancer, there is still a huge unmet need for effective treatment to stop metastasis which accounts for 90% of deaths due to cancer. A major focus of our lab is to study how cancer cells and immune cells such as macrophages and dendritic cells influence the growth and functions of each other in advanced stage solid tumors by integrating recently developed proteomics and computational methods with specific cellular system (Gujral et al., PNAS, 2014, Gujral et al., Cell, 2014). In our lab, we leverage different data-driven approaches (e.g. Protein arrays, high throughput live cell imaging, screening tools) to inform the work of focused biology which utilizes conventional tools including transgenic murine models, molecular and biochemical approaches. The goal is to be able to study cell system as a whole and at microscopic levels in order to find solutions for cancer and other diseases.
Successful candidates will have: